A Dengue Viral infection is a potentially life-threatening infection. The primary and secondary infections with the dengue virus exhibit different clinical profiles. The primary infection, dengue fever, is associated with mild to high fever. The secondary infection, Dengue Hemorrhagic Fever (DHF), often results in high fever, hemorrhage, and circulatory failure.
Primary infections -IgM antibodies are found by the 5th day of infection and remain in circulation for 30 - 60 days, whereas IgG antibodies show up by the 14th day of infection and persist for life. Meanwhile NS1 antigen is
found from the first day and up to 9 days after onset of fever in blood sample of primary or secondary dengue infected patients.
In contrast, during secondary dengue viral infections, specific IgG and IgM levels significantly increase by 1- 2 days and the 20th day after infection, respectively. Thus, different profiles of humoral immune responses in primary and secondary dengue viral infections can be used for differential diagnosis, which is of clinical significance in predicting progression and prognosis of the disease.
|No||Product Desc||Qty Per Box||Catalogue No||Intend Purpose|
|1||Dengue Test Kit (IgG, IgM )||40 Test||DNG 413 Ab||Deferential detection of IgG & IgM antibodies to dengue virus 1-4 serotypes in human serum, plasma and/or whole blood samples.|
|2||Dengue NS 1||40 Test||DNG 413 Ag||Qualitative detection of Dengue NS1 antigen in human blood, serum or plasma sample between 1-9 days in both primary & Secondary infection|
|3||Dengue Combo (NS1/IgG, IgM)||25 Test||DNG 413 Combo||Differential detection of IgG/IgM antibody and NS1 antigen to dengue virus 1,2,3 &4 serotypes in whole blood, serum or plasma samples.|